Publications by authors named "G De Rubeis"

Background: Intracranial atherosclerosis accounts for about 8% of all strokes in Western societies but the influence of arterial calcification on plaque instability is a topic on ongoing debate.

Purpose: Explore the association between the presence and burden of calcium in atherosclerotic plaques among intracranial arteries with the risk of clinical or silent stroke events through a systematic review and meta-analysis.

Data Sources: Adhering to PRISMA guidelines, studies from PubMed and Embase were analyzed up to May 2024.

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Article Synopsis
  • AgeTech is an emerging sector that utilizes various technologies like mobile tech, robotics, and smart home systems to improve the lives of older adults.
  • While it offers opportunities to empower seniors and improve their quality of life, significant ethical challenges must be addressed.
  • The articles in this collection aim to explore these ethical issues, particularly around AI and robotics, and provide strategies for developing technology that supports the health and well-being of older individuals.
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  • Young people face heightened mental health risks, worsened by COVID-19, and digital tools like apps and chatbots are emerging as helpful, stigma-free solutions, although they raise ethical concerns due to a lack of regulations.
  • The study aims to explore the ethical implications of gamified digital mental health interventions for youth, highlighting the importance of integrating these tools into existing mental health frameworks.
  • The review analyzed 38 research publications, focusing on key ethical considerations such as research ethics, privacy, empowerment, cultural sensitivity, and the socioeconomic impacts of these digital interventions.
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Article Synopsis
  • - The study aimed to explore how acute kidney injury (AKI) affects 3-month mortality rates in patients with acute ischemic stroke who underwent mechanical thrombectomy (MT).
  • - After reviewing 3,314 studies, only 18 met the criteria for analysis, ultimately focusing on 3,229 patients, finding a pooled odds ratio for mortality at 3 months in AKI patients to be 5.8.
  • - Results indicated that AKI significantly increased mortality risk, with diabetes as a contributing factor, whereas younger age and less contrast media appeared to be protective factors.
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Aim: To investigate the optimum antiplatelet therapy regimen (APTR) for emergent carotid artery stenting following mechanical thrombectomy (MT) in stroke patients with tandem occlusion.

Methods: A literature search was performed on Pubmed/OVID/Cochran's CENTRAL database for studies from 2015 to 2022. Patient characteristics, antiplatelet regimen type, mTICI, 90 days-mRS, acute in-stent thrombosis (AIST), mortality, intracranial hemorrhage (ICH), and sample size were recorded.

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