Publications by authors named "G D Tansley"
Article Synopsis
- Impaired primary hemostasis and abnormal blood vessel growth (angiogenesis) contribute to gastrointestinal bleeding in patients using continuous-flow left ventricular assist devices (CF-LVADs) in a "two-hit hypothesis."
- A study examined the effects of acute exercise on blood samples from 22 CF-LVAD patients, measuring changes in hemostatic and angiogenic biomarkers.
- Results showed that acute exercise significantly increased platelet count and function, as well as various factors related to blood clotting and vessel growth, suggesting potential benefits for GI bleeding management in these patients.
Purpose: Mammography, breast ultrasound (US), and US-guided breast biopsy are essential services for breast cancer early detection and diagnosis. This study undertook a comprehensive evaluation to determine population-level access to these services for breast cancer early detection and diagnosis in Nigeria using a previously validated geographic information system (GIS) model.
Methods: A comprehensive list of public and private facilities offering mammography, breast US, and US-guided breast biopsy was compiled using publicly available facility data and a survey administered nationally to Nigerian radiologists.
Extracorporeal life support in trauma: Indications and techniques.
J Trauma Acute Care Surg
January 2024
Article Synopsis
- ECLS in trauma is crucial for effective patient care and resource management, with a review conducted at a tertiary trauma center to refine its use.
- A study of 25 ECLS patients revealed successful application with 19 surviving the procedure, highlighting the importance of multidisciplinary consensus on ECLS indications.
- Three main indications for ECLS were identified: gas exchange for lung injuries, extended damage control for severe cases, and circulatory support, emphasizing the need for advanced planning and standardized techniques.
Continuous monitoring of left ventricular stroke work (LVSW) may improve the medical management of patients with rotary left ventricular assist devices (LVAD). However, implantable pressure-volume sensors are limited by measurement drift and hemocompatibility. Instead, estimator algorithms derived from rotary LVAD signals may be a suitable alternative.
View Article and Find Full Text PDFDue to the high treatment costs associated with durable ventricular assist devices, an intra-ventricular balloon pump (IVBP) was developed to provide low-cost, short-term support for patients suffering from severe heart failure. It is imperative that intraventricular flow dynamics are evaluated with an IVBP to ensure stagnation points, and potential regions for thrombus formation, are avoided. This study used particle image velocimetry to evaluate flow patterns within the left ventricle of a simulated severe heart failure patient with IVBP support to assess left ventricle pulsatility as an indicator of the likelihood of flow stasis.
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