Publications by authors named "G D Ogle"
Introduction: There is little published information on type 1 diabetes (T1D) in children in Yemen. We aimed to identify the clinical characteristics, biomarkers and diabetic ketoacidosis (DKA) at diagnosis of T1D among children and adolescents in a diabetes centre in Sana'a, Yemen.
Methods: A total of 485 children and adolescents aged ≤18 years diagnosed with T1D during the period 2010-2020 were included in the study.
Milestone achievement for global access to blood glucose meters and test strips.
Lancet Diabetes Endocrinol
March 2024
Article Synopsis
- Researchers analyzed HLA genotypes in 99 type 1 diabetes (T1D) patients and 200 control subjects from Mali using next-generation sequencing, discovering strong associations between several HLA loci and T1D, primarily in class II genes.
- The study found that certain alleles like HLA-DRB1*03:01 and HLA-B*27:05 are linked to T1D risk, although previous findings suggested different effects, indicating potential complexities related to genetic linkages in this population.
- Amino acid-level analyses indicated that the HLA-C locus shows unique polymorphisms compared to HLA-A and HLA-B, suggesting it may have a distinct influence on T1D risk, highlighting
Aim: There are no data on type 1 diabetes (T1D) incidence and prevalence in Burkina Faso. We aimed to determine these in persons aged <25 years (y) since the implementation of Life for a Child (LFAC) program in 2013.
Patients And Methods: Data were collected from the prospective program register.