[Pregnancy and diabetes mellitus].

The dynamics of the placental lactogenic hormone level, insulin requirements, and glycaemia during pregnancy was studied in diabetes I and II patients and diabetic pregnancies. Fructose amine and C-peptide levels in maternal and neonatal blood were measured in different diabetes types. The risk of diabetes I development in relation to the incidence of the HLA-system antigens was assessed.

[Content of placental lactogen in the blood of pregnant women with diabetes mellitus].

The content of placental lactogenic hormone (PLH), one of the indices of the hormonal function of the placenta, was studied in the blood of pregnant women suffering from diabetes mellitus, depending on the compensation of the disease and the presence of complications in pregnancy. Despite the high weight of placenta, usually observed in this pathology in pregnant women, the blood PLH level did not significantly exceed that in normally coursing pregnancy. In case of decompensated diabetes mellitus there was a significantly lower blood PLH level in comparison with that in the compensated one, this pointing to the direct influence of metabolic disturbances characteristic of decompensated diabetes mellitus on the hormonal function of the placenta.