Publications by authors named "G D Burchard"
Diarrhoea is a frequent symptom associated with travelling to tropical regions, but the cause is often not found. Epidemiology was assessed including up-to-date real-time PCR approaches.We analysed datasets of 528 patients who presented at the Bernhard Nocht Institute for Tropical Medicine in Hamburg, Germany, between 2006 and 2010 for screening purposes or because of diarrhoea.
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- Japanese encephalitis is a serious mosquito-borne disease caused by a flavivirus, and vaccination with the IC51 vaccine is recommended for people at risk, particularly travelers from Europe and the USA.
- A systematic review analyzed 32 studies on the immunogenicity and safety of IC51, revealing high seroprotection rates (up to 100% in some groups) but also significant variability in study quality and design.
- While IC51 has been shown to be safe, with serious adverse events below 5%, the evidence is limited, highlighting the need for more rigorous randomized controlled trials, especially focusing on at-risk populations.
[Travel vaccinations for certain groups of persons].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
January 2020
The number of international travelers has been continuously increasing in recent decades. Among travelers, there are more and more people at an increased risk for acquiring diseases that could be prevented by vaccines or for the development of a severe course of disease. Risk groups in travel medicine are senior travelers, children, pregnant and breast-feeding women, persons with pre-existing medical conditions, and persons who visit their friends and relatives abroad (VFR).
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