Publications by authors named "G D'Ottavio"

Article Synopsis
  • * The study explored how microglia, a type of immune cell in the brain, influence these synaptic changes after cocaine withdrawal and found that depleting microglia blocked cocaine-induced alterations.
  • * Findings suggest that microglia are crucial for synaptic changes in NAc during withdrawal, indicating potential for targeting them in relapse prevention treatments.
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Heroin is an opioid agonist commonly abused for its rewarding effects. Since its synthesis at the end of the nineteenth century, its popularity as a recreational drug has ebbed and flowed. In the last three decades, heroin use has increased again, and yet the pharmacology of heroin is still poorly understood.

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Objective: This study aims to assess accuracy and clinical utility of postmortem radiological exams [Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and Radiography (XR)] after termination of pregnancy at <23 weeks' gestation for congenital fetal malformations in comparison to autopsy.

Study Design: This a prospective single-center study on fetuses underwent termination of pregnancy for fetal defects. Overall concordance between any radiological exam and autopsy was evaluated.

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