Publications by authors named "G Cuesta"

Introduction: There is no reliable microbiological marker to guide responses to antiviral treatment in kidney transplant recipients (KTR) with COVID-19. We aimed to evaluate the dynamics of subgenomic RNA (sgRNA) RT-PCR before and after receiving treatment with remdesivir compared with genomic RNA (gRNA) RT-PCR and its use as a surrogate marker of viral replication.

Methods: We analyzed gRNA and sgRNA at baseline and after remdesivir treatment in KTR who received remdesivir for SARS-CoV-2 infection from November 2021 to February 2022.

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Article Synopsis
  • * Compared to conventional diagnostic tools and the Biofire FilmArray ME Panel, the QIAstat-Dx ME demonstrates high sensitivity (96.43%) and specificity (95.24%) in identifying pathogens.
  • * The results indicate a strong correlation between the QIAstat-Dx ME panel and traditional methods, suggesting it is a reliable rapid-PCR technique for ME diagnosis.
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Background: We aimed to describe a cohort of hematologic patients with COVID-19 treated with antivirals early.

Methods: Non-interventional chart review study. Comparison of baseline characteristics and outcomes in high-risk hematologic patients treated with remdesivir between December 2021 and April 2022 versus those treated with nirmatrelvir/ritonavir between May and August 2022.

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