Publications by authors named "G Couderc"

Article Synopsis
  • The COMET biobank project collects special tissue and blood samples from overweight patients to help with research on insulin sensitivity.
  • They set up a system to make sure all the samples are good quality and that the collection process is done the right way.
  • The results showed that the samples were collected properly, with good quality of DNA, RNA, and tissues, ensuring the project can be used for scientific studies safely.
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Purpose: To assess risk factors of rejection after penetrating keratoplasty (PKP).

Methods: This retrospective monocentric study assessed risk factors for rejection in patients who underwent PKP at Montpellier University Hospital between June 2005 and September 2018. Graft and donor data were obtained from our tissue bank in Montpellier.

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Background: Mesenchymal stromal cells (MSCs) represent an interesting tool to improve pancreatic islet transplantation. They have immunomodulatory properties and secrete supportive proteins. However, the functional properties of MSCs vary according to many factors such as donor characteristics, tissue origin, or isolation methods.

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Article Synopsis
  • Standard operating rooms (SOR) are often thought to be the safest for tissue procurement, but using non-operating dedicated rooms (NODR) or even ICU might be more efficient and less costly when no organ retrieval occurs.
  • The study analyzed tissue retrieval data from 2,535 deceased donors to assess the risk of microbial contamination based on different locations (ICU, SOR, NODR).
  • Results indicated that retrieval in NODR had a significantly lower risk of contamination, suggesting that using dedicated rooms or ICU for tissue procurement could reduce contamination rates and might eliminate the need to transfer patients from ICU to SOR.
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