Publications by authors named "G Consoli"
We investigate the therapeutic potential of Aloin A and Aloin B, two natural compounds derived from Aloe vera leaves, focusing on their neuroprotective and anticancer properties. The structural differences between these two epimers suggest that they may exhibit distinct pharmacological properties. Our investigations revealed that both epimers are not stable in aqueous solution and tend to degrade rapidly, with their concentration decreasing by over 50% within approximately 12 h.
View Article and Find Full Text PDFPilates-based programs can help pregnant women deal with the physical and psychological burden derived by major changes in their body. This study was designed to primarily test, in pregnant women, the dose-response and health effects of both pre-partum and post-partum, online Pilates-based program on weight control, low back pain (LBP) severity, sleep disturbances, mood and depression levels. A total of 136 pregnant women were screened for eligibility (low-risk pregnancy; aged 18-45 years; single pregnancy; 20-28-week gestational age, normal BMI).
View Article and Find Full Text PDFIn recent decades, ionic liquids (ILs) have garnered research interest for their noteworthy properties, such as thermal stability, low or no flammability, and negligible vapour pressure. Moreover, their tunability offers limitless opportunities to design ILs with properties suitable for applications in many industrial fields. This study aims to synthetise two series of methylimidazolium ILs bearing long alkyl chain in their cations (C9, C10, C12, C14, C16, C18, C20) and with tetrafluoroborate (BF) and the 1,3-dimethyl-5-sulfoisophthalate (DMSIP) as counter ions.
View Article and Find Full Text PDFArticle Synopsis
- Mental disorders are a major global health issue, with depression projected to be the leading contributor to the disease burden by 2030, especially worsened by the COVID-19 pandemic's impact on mental health in adolescents.
- The pandemic has led to long-term effects known as "long-COVID," which include cognitive and psychological symptoms linked to neuroinflammation caused by widespread inflammation.
- Research suggests that the endocannabinoid system (ECS), particularly through the cannabinoid type-2 receptor (CB2R), may offer new treatment options for depression and anxiety, with a focus on β-caryophyllene (BCP) for its anti-inflammatory and antioxidant benefits.
Article Synopsis
- Zero-dimensional boron nitride quantum dots (BNQDs) have promising optical, chemical, and biochemical properties, especially when integrated with carbon, specifically phenolic groups for biomedical applications.
- The first direct synthesis of water-dispersible BNQDs containing phenolic and carboxylic groups is accomplished through a single-step solvent-assisted reaction, and various characterization methods confirm their stability and unique luminescent properties.
- The carbon-BNQDs show biocompatibility with cancer cells, offering protection against oxidative stress, and analyzing mRNA-seq expression provides insight into their protective molecular effects.