Publications by authors named "G Charalambidis"
Article Synopsis
- The study introduces a new hybrid photocatalytic nanomaterial made from porphyrin-carbon dot conjugates that generates hydrogen using visible light.
- The researchers created M-TCPP-NCDots hybrids through amide coupling of metallated tetra-carboxyphenyl porphyrins with nitrogen-doped carbon dots, enabling hydrogen production without needing expensive metallic co-catalysts.
- Key findings highlight that the covalent attachment and zinc-metallation of the porphyrin component are crucial for improving the system's efficiency, presenting a novel method for artificial photosynthesis.
Antimicrobial Potency of Fmoc-Phe-Phe Dipeptide Hydrogels with Encapsulated Porphyrin Chromophores Is a Promising Alternative in Antimicrobial Resistance.
Biomolecules
February 2024
Article Synopsis
- Antimicrobial resistance (AMR) is a major global health threat caused by the overuse of antibiotics, highlighting the need for new antimicrobial solutions.
- Researchers are exploring porphyrins and metalloporphyrins, which have antimicrobial properties activated by light, as potential agents for battling this issue.
- This study focuses on embedding these porphyrins into peptide hydrogels, which are biocompatible and effective against both Gram-positive and Gram-negative bacteria, with zinc porphyrins showing the highest efficacy.
Conjugates of chlorins with β-cyclodextrin connected either directly or via a flexible linker were prepared. In aqueous medium these amphiphilic conjugates were photostable, produced singlet oxygen at a rate similar to clinically used temoporfin and formed irregular nanoparticles via aggregation. Successful loading with the chemotherapeutic drug tamoxifen was evidenced in solution by the UV-Vis spectral changes and dynamic light scattering profiles.
View Article and Find Full Text PDFThere is a growing interest in developing dye-sensitized photocatalytic systems (DSPs) to produce molecular hydrogen (H ) as alternative energy source. To improve the sustainability of this technology, we replaced the sacrificial electron donor (SED), typically an expensive and polluting chemical, with an alcohol oxidation catalyst. This study demonstrates the first dye-sensitized system using a diketopyrrolopyrrole dye covalently linked to 2,2,6,6-tetramethyl-1-piperidine-N-oxyl (TEMPO) based catalyst for simultaneous H evolution and alcohol-to-aldehyde transformation operating in water with visible irradiation.
View Article and Find Full Text PDFWe developed dye-sensitized photocatalytic systems (DSPs) by utilizing porphyrins as a photosensitizer (PS) or as a photosensitizer-catalyst (PS/CAT) upon their chemisorption onto platinum-doped titanium dioxide nanoparticles (Pt-TiO NPs). The DSPs coated with Pt-Tc3CP (PS/CAT entity) exhibited a record-high stability (25 500 TONs) and H evolution activity (707 mmol g h) compared to similar DSPs in the literature.
View Article and Find Full Text PDF