Publications by authors named "G Chand"
Background: The role of the silkless1 (sk1) gene in developing silkless baby corn, a distinctive trait in maize has been investigated. So far, no sk1 gene-specific marker has been available for accelerated development of silkless baby corn hybrids.
Methods & Results: We developed sk1 gene-based markers and validated them in backcross (BC) and F segregating generations, revealing a polymorphic marker corresponding to a silkless phenotype.
The objective of this systematic review and meta-analysis was to evaluate the efficacy and long-term outcomes of arthroscopic meniscus repair, focusing on success, failure, and reoperation rates. A comprehensive literature search was conducted across PubMed, EMBASE, Cochrane Library, and Scopus, including studies that involved patients undergoing arthroscopic meniscus repair with a minimum follow-up of two years. The quality of the included studies was assessed using the Cochrane Risk of Bias Tool for randomized controlled trials and the Newcastle-Ottawa Scale for observational studies.
View Article and Find Full Text PDFBackground: Nausea and vomiting are one of the common and distressing side effects of chemotherapy in breast cancer patients often impacting their quality of life and treatment adherence. The purpose of this systematic review and meta-analysis was to determine whether acupressure is effective in treating breast cancer patients' acute nausea and vomiting brought on by chemotherapy as well as delayed nausea and vomiting.
Methods: We systematically searched for Randomized controlled trials and quasi-experimental studies in PubMed, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Clinical Key, Web of Science, EMBASE, and Scopus.
Article Synopsis
- Regulation of dopamine activity is crucial for treating conditions like schizophrenia, with LB-102 being a new dopamine D/5-HT inhibitor aimed at this purpose.
- The study measured how effectively LB-102 occupied dopamine receptors in healthy volunteers using PET scans at various doses, finding that 50 mg consistently provided the desired occupancy over 24 hours.
- Results indicated that while steady dosing led to consistent receptor occupancy, the relationship between receptor occupancy and plasma concentrations was different than usual, and LB-102 was safe and well-tolerated across all tested doses.
Article Synopsis
- Maize zeins are lacking in essential amino acids, but the floury2 (fl2) mutation enhances the amino acid profile, specifically increasing methionine and lysine in kernels.
- Researchers sequenced the fl2 gene in various inbred lines and identified multiple genetic variations, including a critical C to T transversion that changes alanine to valine, leading to a unique PCR-based marker for selecting the fl2 mutant allele.
- The study revealed significant genetic diversity among the inbred lines, identified 29 haplotypes of the fl2 gene, and provided insights valuable for molecular breeding in maize aimed at improving nutritional quality.