Publications by authors named "G Chami"
Background: Periportal fibrosis is a severe morbidity caused by both current and past exposure to intestinal schistosomes. We aimed to assess the association between current infection status and intensity of Schistosoma mansoni, Schistosoma japonicum, or Schistosoma mekongi with periportal fibrosis.
Methods: In this systematic review and meta-analysis, we searched the Cochrane Central Register of Controlled Trials, Embase, Global Health, Global Index Medicus, and MEDLINE from database inception to June 18, 2024.
Article Synopsis
- * A study in Uganda involving 2867 individuals revealed a 15-year gap between peak water contact and infection ages, showing minimal correlation between individual water contact and infection rates.
- * Key findings include that adults often have higher water contact than children, with factors like age, occupation, and proximity to water bodies influencing contact patterns, highlighting the need for targeted interventions in at-risk groups.
Article Synopsis
- - The study investigated the relationship between schistosomiasis infection and periportal fibrosis (a liver condition) among 2834 individuals aged 5-90 in Uganda, using ultrasound and various diagnostic tests.
- - Findings revealed that 12.1% of participants had periportal fibrosis, while 43.4% were infected with schistosomiasis, although there was no direct correlation between infection intensity and the likelihood of developing fibrosis.
- - Notably, the risk of periportal fibrosis increased with age, significantly rising until about 45 years, then stabilizing or decreasing thereafter, highlighting the importance of considering age in future morbidity assessments for schistosomiasis.
Background: In the first year of roll-out, vaccination for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prevented almost 20 million deaths from coronavirus disease 2019 (COVID-19). Yet, little is known about the factors influencing access to vaccination at the individual level within rural poor settings of low-income countries. The aim of this study was to examine determinants of vaccine receipt in rural India.
View Article and Find Full Text PDFBackground: Abdominal ultrasound imaging is an important method for hepatic schistosomiasis diagnosis and staging. Several ultrasound staging systems have been proposed, each attempting to standardise schistosomal periportal fibrosis (PPF) diagnosis. This review aims to establish the role of ultrasound in the diagnosis and staging of schistosomal PPF, and to map the evolution of ultrasound staging systems over time, focusing on internal validation and external reproducibility.
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