The aim of this study was to estimate the radioactive risk for surgical staff performing radioguided sentinel lymph node (SN) biopsy and to calculate the contamination level in the operating room for assessment of the possible need for specific radiation protection procedures. We studied 20 patients who were selected for quadrantectomy and SN biopsy. The day before surgery a volume of 0.
View Article and Find Full Text PDFThe aim of the study was to evaluate in our institute the technique of sentinel node (SN) identification and biopsy in the surgical treatment of early breast cancer. Between June 1998 and November 1999 54 patients (age range, 31-75 years) where studied. Inclusion criteria were age less than 75 years, indication for conservative surgery, absence of palpable axillary nodes, Karnofksy index >70.
View Article and Find Full Text PDFWe compared the results of bone marrow scintigraphy (SMO) with those of conventional bone scintigraphy (SO) obtained in patients suffering of malignant neoplasms. SMO was carried out using nanometer-sized particles (nanocolloid) labelled with 99mTc, known to target the phagocitic properties of the medullar reticulo-endothelial cells. The results of the two investigations carried out in 148 patients agreed with each other.
View Article and Find Full Text PDFRandom additional treatment with Thymopentine was administered to a group of 46 mastectomised women in order to assess its possible anti-leucopenic efficacy in relation to cytotoxicity caused by anti-blastic drugs. Results reveal a certain degree of efficacy in reducing the incidence of leucopenia when treatment was administered continuously from the start to the end of chemotherapy. This aspect plays an extremely important role in avoiding the protraction of the normal interval between one cycle of anti-blastic chemotherapy and the next.
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