Publications by authors named "G Carneiro"
Background: Streptococcus pneumoniae (pneumococcus) is a common cause of respiratory and invasive infections in humans. PCV13, a pneumococcal conjugate vaccine used globally, is highly effective against diseases caused by pneumococcal serotypes included in its formulation. However, one of them, the serotype 3 (ST3) is still being relatively commonly isolated from patients, suggesting an escape from vaccine-induced immunity.
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- - Endometriosis, affecting about 10% of individuals assigned female at birth, is difficult to diagnose and often requires surgical or MRI imaging methods, with MRI being quicker but less precise.
- - A significant diagnostic indicator is the obliteration of the Pouch of Douglas, yet even experienced clinicians find it hard to accurately classify this from MRI images, which makes training reliable AI models a challenge.
- - The paper introduces the HAICOMM methodology, which combines multi-rater and multi-modal learning with human-AI collaboration, leading to more accurate diagnoses of endometriosis compared to traditional methods and improving classification accuracy.
Diseases caused by Streptococcus pneumoniae (pneumococcus) produce a great impact on public health, killing about one million people annually despite available vaccines. Recent research has revealed that the pneumococcus produces extracellular vesicles (pEVs), which display selective cargo and hold potential for vaccine development. Here, we evaluated the immunogenicity and protective potential of pEVs derived from a non-encapsulated pneumococcal strain (R6) using murine models of pneumococcal colonization and invasive pneumonia.
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- Trema micranthum, a plant from the Cannabaceae family, shows potential as a new source of cannabinoids like CBD, amid the regulatory issues surrounding Cannabis sativa due to THC content.
- This study used advanced UHPLC-HRMS/MS techniques to analyze different parts of the plant—fruits, leaves, inflorescences, and stems—for the presence of CBD, THC, and their acidic precursors (THCA A and CBDA).
- The results revealed significant levels of cannabinoids, especially in the leaves (4.43 µg/g CBD, 1.05 µg/g THC), indicating that Trema micranthum could serve as a viable alternative source for cannabinoid research and production.
Is platelet-rich plasma effective in treating uterine inflammation in jennies inseminated with cryopreserved donkey semen?
Theriogenology
January 2025
Article Synopsis
- - The study examines the impact of platelet-rich plasma (PRP) on uterine inflammation and pregnancy rates in jennies (female donkeys) inseminated with frozen donkey semen, which generally shows lower success in jennies compared to mares.
- - Three groups of jennies were tested: a control group with no treatment, a group receiving a single PRP infusion, and a group getting double PRP infusions around ovulation and artificial insemination (AI).
- - Results indicated that while S-PRP reduced intrauterine fluid (IUF) accumulation shortly after AI, no significant differences were observed in pregnancy rates among groups, suggesting PRP treatments did not effectively improve outcomes for jennies