Publications by authors named "G Carignani"
Article Synopsis
- The study aims to understand how psychiatric disorders, ADHD symptoms, and emotional dysregulation affect weight loss after bariatric surgery in obese patients.
- Conducted at the Obesity Center of Pisa University Hospital, the research involved 99 participants, with follow-up evaluations focusing on psychiatric diagnoses, ADHD symptoms, and emotional regulation.
- Results indicate that individuals with insufficient weight loss post-surgery had higher rates of binge eating disorder and emotional dysregulation, while factors like older age and higher pre-surgery BMI were linked to poorer weight loss outcomes.
Purpose: We aimed at investigating the lifetime prevalence of mood, eating and panic disorders in a large sample of obese patients referred to bariatric surgery. We also explored the patterns of psychiatric comorbidity and their relationship with Body Mass Index (BMI).
Methods: The sample was composed of patients consecutively referred for pre-surgical evaluation to the Obesity Center of Pisa University Hospital between January 2004 and November 2016.
Background: Obese patients seeking bariatric surgery are known to show high rates of mental disorders, mainly mood and eating disorders. The aim of the present study is to evaluate psychiatric comorbidities, affective temperamental dimensions, emotional dysregulation and impulsivity in a sample of obese bariatric patients, exploring the differences between obese patients with and without mood disorders (MD).
Methods: A total of 69 obese patients were consecutively enrolled between March and November 2019 during the presurgical evaluation routinely performed before the bariatric intervention.
In the last decades, obesity has become a major concern for clinical and public health. Despite the variety of available treatments, the outcomes remain-by and large-still unsatisfactory, owing to high rates of nonresponse and relapse. Interestingly, obesity is being associated with a growing surge of neuropsychiatric problems, certainly related to the pathogenesis of this condition, and likely to be of great consequence as for its treatment and prognosis.
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- - Loss-of-function mutations in the SOX2 gene are primarily linked to eye disorders like anophthalmia and microphthalmia, but can also lead to non-ocular issues such as growth problems and developmental delays.
- - A study involving patients with intellectual disabilities, but no eye abnormalities, found no significant SOX2 mutations in 192 tested individuals, indicating SOX2 mutations are not a major cause of intellectual disability without associated eye conditions.
- - The investigation highlights how "genotype first" approaches, which analyze genetic information without prior assumptions, can reveal the broader impacts of certain genes like SOX2, showing they can be involved in conditions beyond their traditionally recognized traits.