Publications by authors named "G Candy"
Background: Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer characterized by an immunosuppressive microenvironment. Patients from specific ethnicities and population groups have poorer prognoses than others. Therefore, a better understanding of the immune landscape in such groups is necessary for disease elucidation, predicting patient outcomes and therapeutic targeting.
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- Mesenteric cysts are benign tumors found in the mesentery and are quite rare, occurring in about 1 in 20,000 children, typically located near the small bowel.
- Most patients with mesenteric cysts experience no symptoms, but some may have vague issues like abdominal pain or more serious complications, including volvulus, which can present differently in infants and older children.
- In a study of two cases, an infant presented with an acute abdomen and an enterogenous cyst, while a child had a chylous cyst without acute symptoms, highlighting the importance of clinical differences for diagnosis.
Background: Gallbladder cancer (GBC) is a lethal cancer with a poor prognosis. The lack of specific and sensitive biomarkers results in delayed diagnosis with most patients presenting at late stages of the disease. Furthermore, there is little known about the molecular mechanisms associated with GBC, especially in patients of African ancestry.
View Article and Find Full Text PDFBackground: The negative appendicectomy rate (NAR) is defined as the proportion of surgically removed appendices that are pathologically normal. The acceptable NAR has been a debated issue. Previously, a higher rate was accepted, whilst newer thinking favours a lower rate.
View Article and Find Full Text PDFPancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a characteristic dysregulated metabolism. Abnormal clinicopathological features linked to defective metabolic and inflammatory response pathways can induce PDAC development and progression. In this study, we investigated the metabolites and lipoproteins profiles of PDAC patients of African ancestry.
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