Publications by authors named "G Calaminus"
Purpose: The shift from child-centered to adult-focused healthcare presents social and psychological challenges for adolescents and young adults with chronic conditions, which can affect their participation in follow-up care. This study aims to investigate the factors that influence patient-driven motivations for adhering to follow-up recommendations, while also exploring the barriers and supports that impact the transition process for pediatric cancer survivors.
Methods: We developed interview guidelines grounded in the Theory of Planned Behavior (TPB) and the stereotype priming model (SPM).
Article Synopsis
- The European Cancer Organisation's Essential Requirements for Quality Cancer Care (ERQCC) provide guidance on how to improve cancer treatment, focusing on ovarian cancer specifically.
- Ovarian cancer patients experience low cure rates due to inconsistent treatment and a need for specialized care, which should be provided in dedicated centers by qualified professionals.
- Centralized, patient-centered care throughout the entire treatment journey is essential for better outcomes but is not yet widely implemented across many European countries.
Adolescents and young adults (AYAs; ages 15-39 years) are a vulnerable population facing challenges in oncological care, including access to specialized care, transition of care, unique tumor biology, and poor representation in clinical trials. Brain tumors are the second most common tumor type in AYA, with malignant brain tumors being the most common cause of cancer-related death. The 2021 WHO Classification for central nervous system (CNS) Tumors highlights the importance of integrated molecular characterization with histologic diagnosis in several tumors relevant to the AYA population.
View Article and Find Full Text PDFBackground: In Germany, around 2.250 children and adolescents are diagnosed with cancer each year. Despite generally positive long-term survival rates, many patients must cope with late effects of the disease and its treatment.
View Article and Find Full Text PDFArticle Synopsis
- - The SIOP-CNS-GCT-II European trial studied the effects of age on acute toxicity from chemotherapy in patients with central nervous system germ cell tumors, using various chemotherapy regimens based on tumor type.
- - Analysis included 296 patients across three age groups: children (≤11 years), adolescents (12-17 years), and adults (≥18 years), revealing that adults experienced lower rates of severe adverse events compared to adolescents despite similar chemotherapy dosages.
- - The study concluded that adults can safely tolerate intensive chemotherapy protocols with less toxicity than adolescents, indicating a need for further investigation into how age influences chemotherapy-related toxicity.