Publications by authors named "G C Windham"

Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery ("peripregnancy") with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30-68 months with ASD symptoms (i.

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Objectives: To examine associations between pregnancy planning and autism spectrum disorder (ASD) in offspring.

Methods: The Study to Explore Early Development (SEED), a multi-site case-control study, enrolled preschool-aged children with ASD, other DDs, and from the general population (POP). Some children with DDs had ASD symptoms but did not meet the ASD case definition.

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Article Synopsis
  • Over two-thirds of pregnant women in the U.S. have low Vitamin D levels, which can negatively affect fetal health, and various environmental pollutants may influence these levels.
  • The study analyzed serum samples from 421 women in Southern California to explore the relationship between prenatal exposure to multiple environmental chemicals and Vitamin D concentrations during mid-pregnancy.
  • Findings showed a general trend where combined exposures to certain pollutants were linked with lower Vitamin D levels, emphasizing the importance of considering chemical mixtures rather than individual pollutants in research.
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Background: Per- and polyfluoroalkyl substances (PFAS), endocrine disrupting chemicals with worldwide exposure, cause changes in mammary gland development in rodents. A few human studies report delay in pubertal events with increasing perfluorooctanoic acid (PFOA) exposure, but to our knowledge none have examined reproductive hormone levels at thelarche.

Methods: In a cohort of Greater Cincinnati (GC) and San Francisco Bay Area (SFBA) girls recruited at 6-8 years of age, clinical examinations were conducted annually or semiannually with sequential Tanner staging.

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Background: Studies evaluating the association between prenatal ultrasounds and autism spectrum disorder (ASD) have largely produced negative results. Concern remains due to the rising identification of children with ASD and ultrasound use.

Objective: To evaluate the association between prenatal ultrasound use and ASD.

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