[An older female patient with refractory anemia and hemochromatosis].

Case History And Clinical Findings: A 69-year-old woman was admitted because of a normocytic anemia. One year before an acute B19 parvovirus infection had been diagnosed, but the anemia was attributed to intestinal bleeding caused by a dysplastic colonic polyp. However, anemia persisted despite polypectomy.

[Tracheobronchopathia osteochondroplastica: an uncommon cause of retention pneumonia in an elderly patient].

A 79 years old patient without preexisting pulmonary disease was admitted due to pneumonia and hemoptysis. Despite intravenous antibiotic therapy he did not recover and still suffered from fever and dyspnea six days later. Fiberoptic bronchoscopia was performed in order to exclude poststenotic pneumonia.

[A young man with adynamia, subepicardial ischemia and sleep apnea].

History And Clinical Findings: A 44-year-old manager presented himself for the assessment of nocturnal apnoea. He reported increasing lack of drive and nightly angina pectoris.

Investigations: Polysomnography indicated obstructive apnoea and hypopnoea with a respiratory disturbance index of 29.

Sarcoidosis and common variable immunodeficiency. A case of a malignant course of sarcoidosis in conjunction with severe impairment of the cellular and humoral immune system.

The occurrence of sarcoidosis in combination with common variable immunodeficiency (CVID) has been described in a small number of patients. In these patients, sarcoidosis consisted of lymphadenopathy, mild to moderate pulmonary involvement and hepatosplenomegaly. However, severe and rapidly progressive pulmonary fibrosis in combination with a severe defect of the cellular and humoral immune system has not been described yet.

Phase II study of anti-CD4 idiotype vaccination in HIV positive volunteers.

A clinical phase II trial of postinfectional idiotype vaccination was performed in early stage HIV + volunteers. The mAb 13B8.2 is directed against the CDR3-homologous CD4/D1 region implicated in HIV-gp120 binding.