Publications by authors named "G C Mead"
This erratum corrects errors that appear in Opt. Express31, 5042 (2023).10.
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- Atrial fibrillation (AF) is a common heart rhythm disorder, and cardioversion is a method used to return the heart to its normal rhythm through medications or electrical shocks.
- The study aimed to evaluate the effectiveness and safety of both pharmacological and electrical cardioversion treatments for AF and related conditions.
- Researchers analyzed data from 112 randomized controlled trials involving nearly 16,000 patients, noting that many trials had a high risk of bias and varying demographics among participants.
Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not completely understood. Here we demonstrate that Neuropilin-1 (NRP1) and Plexin-A1 and Plexin-A4 are upregulated on stimulated CD8 T cells, allowing tumour-derived SEMA3A to inhibit T cell migration and assembly of the immunological synapse.
View Article and Find Full Text PDFBackground: Three large randomized controlled trials of fluoxetine for stroke recovery have been performed. We performed an individual patient data meta-analysis (IPDM) on the combined data.
Methods: Fixed effects meta-analyses were performed on the combined data set, for the primary outcome (modified Rankin scale (mRS) at 6 months), and secondary outcomes common to the individual trials.