Publications by authors named "G C Mansueto"

Introduction: The Mental Pain Questionnaire (MPQ) was developed using a clinimetric approach to bring together the key features of mental pain into a single, brief, transdiagnostic scale. The present study aims at extending the validation of the MPQ to people from three different clinical settings.

Methods: A multicentre, cross-sectional study on adults diagnosed with migraine (n = 256), systemic sclerosis (n = 219), or mental disorders (n = 138) was conducted.

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Using the Elaborated Intrusion Theory of Desire and the Self-Regulatory Executive Function model of psychopathology as bases, this study explored whether metacognitive beliefs and desire thinking (DT) are associated with higher levels of Compulsive Sexual Behavior (CSB). A total of 1185 participants from the general population were included in the study (mean ± SD age = 25.32 years ± 5.

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Introduction: Using the self-regulatory executive function model as a basis, this study explored whether, among substance users, metacognitive beliefs and repetitive negative thinking were associated with impulsiveness.

Methods: A total of 100 substance users were recruited. Impulsiveness, metacognitive beliefs, rumination and worry were assessed.

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Article Synopsis
  • Epigenetics plays a significant role in various cancers, including diffuse large B-cell lymphoma (DLBCL), where the expression of genes BMI1, EZH2, and USP22 is being studied for their impact on prognosis.
  • A multiplex digital droplet PCR (ddPCR) method was developed to measure the levels of these genes in RNA from tissue samples, showing high specificity and repeatability.
  • Results indicated that elevated levels of BMI1 and USP22 correlate with worse progression-free survival (PFS) and overall survival (OS) in high-risk DLBCL patients, suggesting these genes could be potential targets for new treatments.
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This study aimed to introduce specific image feature analysis, focusing on pancreatic margins, and to provide a quantitative measure of edge irregularity, evidencing correlations with the presence/absence of pancreatic adenocarcinoma. We selected 50 patients (36 men, 14 women; mean age 63.7 years) who underwent Multi-detector computed tomography (MDCT) for the staging of pancreatic adenocarcinoma of the tail of the pancreas.

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