Leveraging human-centered design and causal pathway diagramming toward enhanced specification and development of innovative implementation strategies: a case example of an outreach tool to address racial inequities in breast cancer screening.

Background: Implementation strategies are strategies to improve uptake of evidence-based practices or interventions and are essential to implementation science. Developing or tailoring implementation strategies may benefit from integrating approaches from other disciplines; yet current guidance on how to effectively incorporate methods from other disciplines to develop and refine innovative implementation strategies is limited. We describe an approach that combines community-engaged methods, human-centered design (HCD) methods, and causal pathway diagramming (CPD)-an implementation science tool to map an implementation strategy as it is intended to work-to develop innovative implementation strategies.

Wearable Capacitive Tactile Sensor Based on Porous Dielectric Composite of Polyurethane and Silver Nanowire.

In recent years, the implementation of wearable and biocompatible tactile sensing elements with sufficient response into healthcare, medical detection, and electronic skin/amputee prosthetics has been an intriguing but challenging quest. Here, we propose a flexible all-polyurethane capacitive tactile sensor that utilizes a salt crystal-templated porous elastomeric framework filling with silver nanowire as the composite dielectric material, sandwiched by a set of polyurethane films covering silver nanowire networks as electrodes. With the aids of these cubic air pores and conducting nanowires, the fabricated capacitive tactile sensor provides pronounced enhancement of both sensor compressibility and effective relative dielectric permittivity across a broad pressure regime (from a few Pa to tens of thousands of Pa).

Prussian blue analog with separated active sites to catalyze water driven enhanced catalytic treatments.

Chemodynamic therapy (CDT) uses the Fenton or Fenton-like reaction to yield toxic ‧OH following HO → ‧OH for tumoral therapy. Unfortunately, HO is often taken from the limited endogenous supply of HO in cancer cells. A water oxidation CoFe Prussian blue (CFPB) nanoframes is presented to provide sustained, external energy-free self-supply of ‧OH from HO to process CDT and/or photothermal therapy (PTT).

Integrating patient voices into the extraction of social determinants of health from clinical notes: ethical considerations and recommendations.

Identifying patients' social needs is a first critical step to address social determinants of health (SDoH)-the conditions in which people live, learn, work, and play that affect health. Addressing SDoH can improve health outcomes, population health, and health equity. Emerging SDoH reporting requirements call for health systems to implement efficient ways to identify and act on patients' social needs.