Publications by authors named "G C Hansen"
Introduction/aims: Spirometry is the conventional means to measure lung function in amyotrophic lateral sclerosis (ALS), but is dependent on patient effort and bulbar strength. We aimed to use electric impedance tomography (EIT), an emerging non-invasive imaging modality, to measure dynamic lung volume changes.
Methods: Twenty-one patients with ALS underwent sitting and supine spirometry for forced vital capacity (FVC), and sitting and supine EIT.
Protocol for a 1-year randomised, controlled, parallel group, open-label trial on the effects and feasibility of time-restricted eating in individuals with type 2 diabetes- The Restricted Eating Time in the Treatment of Type 2 Diabetes (RESET2) trial.
Diabet Med
January 2025
Aim: Time-restricted eating (TRE) limits the time for food intake to typically 6-10 h/day without other dietary restrictions. The aim of the RESET2 (the REStricted Eating Time in the treatment of type 2 diabetes) trial is to investigate the effects on glycaemic control (HbA) and the feasibility of a 1-year TRE intervention in individuals with overweight/obesity and type 2 diabetes. The aim of the present paper is to describe the protocol for the RESET2 trial.
View Article and Find Full Text PDFClimate change is altering the thermal habitats of freshwater fish species. We analyze modeled daily temperature profiles from 12,688 lakes in the US to track changes in thermal habitat of 60 lake fish species from different thermal guilds during 1980-2021. We quantify changes in each species' preferred days, defined as the number of days per year when a lake contains the species' preferred temperature.
View Article and Find Full Text PDFArticle Synopsis
- Zebra mussels are invasive species that can change aquatic ecosystems and food webs, potentially increasing mercury levels in fish, yet their impact in inland lakes hadn't been previously studied.
- In Minnesota lakes with zebra mussels, adult walleye and yellow perch showed mercury levels 72% and 157% higher, respectively, compared to lakes without them, with young fish also having elevated mercury concentrations.
- These higher mercury levels in invaded lakes raise concerns for fisheries management and human health, especially since many walleye exceeded safe consumption thresholds more frequently than in uninvaded lakes.
Background: Humans are subjected to various environmental stressors (bacteria, viruses, pollution) throughout life. As such, an inherent relationship exists between the effect of these exposures with age. The impact of these environmental stressors can manifest through DNA methylation (DNAm).
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