Publications by authors named "G C Freire"

Background: Respiratory tract infections with viral pathogens are frequently identified using the World Health Organization (WHO) case definition of severe acute respiratory infection (SARI), defined as fever of ≥38°Celsius, cough, onset within 10 days, and hospitalization. While there is extensive research in adults, less is known about the WHO SARI case definition performance in children and youth. We aimed to determine the performance of the WHO SARI and modified case definitions in identifying viral respiratory tract infections in hospitalized children and youth.

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Due to the ageing population throughout the world, the rates of older adults suffering from dementia are increasing, requiring a closer look at this population. As a result, the aim of this scoping review is to gather data from the scientific literature on the repercussions of abuse of elderly people with dementia by their caregivers. For this review, Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews was used as a guideline to structure the review topics.

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Objective: To investigate the feasibility of using actigraphy to measure physical activity (pA) and heart rate variability (HRV) as study endpoints in pediatric pulmonary arterial hypertension (PAH) and to compare their performance to 6-minute-walk distance (6MWD), a common primary endpoint used in PAH clinical trials in adults and children who can walk and understand the test process.

Study Design: We conducted a prospective, multicenter, noninterventional study in pediatric PAH patients and healthy children. Actiheart and Fitbit Charge 2 recorded pA and heart rate data.

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Objective: To evaluate the quality of oral health care through indicators in patients undergoing hematopoietic stem cell transplantation for the management of oral mucositis.

Methods: Thirty-five patients were evaluated. Photobiomodulation was performed during the conditioning regimen, 1 day, 5 days, and 10 days after transplantation.

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Article Synopsis
  • The study highlights the significance of reducing low-value care in pediatric trauma, suggesting that it can enhance patient experiences and outcomes while minimizing unnecessary healthcare resource use.* -
  • A retrospective cohort study involving over 10,700 children admitted to trauma centers in a Canadian province was conducted to identify and assess low-value practices in pediatric trauma care.* -
  • The research found 19 low-value practices, with five showing moderate to high frequency and variation across hospitals, indicating a need for standardized care to improve pediatric trauma treatment.*
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