Publications by authors named "G C Chow"

Introduction: Patient-reported outcome measures (PROMs) represent an important part of a comprehensive voice assessment for clinical care and research. Access to multilingual PROMs enables inclusion of information from diverse patient populations. This review compares available translated and validated PROMs for adult dysphonia.

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Circadian clocks respond to temperature changes over the calendar year, allowing organisms to adjust their daily biological rhythms to optimize health and fitness. In , seasonal adaptations are regulated by temperature-sensitive alternative splicing (AS) of () and () genes that encode key transcriptional repressors of clock gene expression. Although () gene encodes the critical activator of circadian gene expression, AS of its transcripts and its potential role in temperature regulation of clock function have not been explored.

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Background: Children with ADHD demand for effective intervention with minimum side effect to improve executive function (EF) and health well-being.

Method: This study used a three-arm partially-blinded randomized controlled trial to test the effects of two different kinds of 8-week game-based training programs (game-based HIIT program, GameHIIT; and game-based structured aerobic exercise program, GameSAE) on EF and other health indicators of children with ADHD, which was compared with a non-treatment control group.

Results: A total of 49 children with ADHD completed the program.

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Article Synopsis
  • DEBCT is a new cell therapy that creates skin grafts from patients’ own iPS cells to treat Dystrophic Epidermolysis Bullosa (DEB).
  • This method combines CRISPR gene editing with cell reprogramming for faster production of corrected cells, leading to effective and diverse skin cell types.
  • Early studies show that these grafts are safe and can effectively improve skin conditions in DEB patients within a month of treatment.
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Circadian clocks respond to temperature changes over the calendar year, allowing organisms to adjust their daily biological rhythms to optimize health and fitness. In , seasonal adaptations and temperature compensation are regulated by temperature-sensitive alternative splicing (AS) of () and () genes that encode key transcriptional repressors of clock gene expression. Although () gene encodes the critical activator of clock gene expression, AS of its transcripts and its potential role in temperature regulation of clock function have not been explored.

View Article and Find Full Text PDF