Publications by authors named "G C Bartoli"
Article Synopsis
- Kidney transplantation is the best treatment for end-stage kidney disease, but long-term success can be affected by issues like recurrence of native kidney diseases such as C3 glomerulopathy (C3GN).
- A case study documented a female kidney transplant recipient whose kidney function declined after 28 years due to two SARS-CoV-2 infections, alongside evidence of chronic rejection and features of C3GN in her recent biopsy.
- The findings suggest that C3GN may have recurred late in this patient as a result of complement activation triggered by the SARS-CoV-2 infections, indicating a potential new risk factor for post-transplant complications.
Article Synopsis
- C3 glomerulopathy is a rare kidney disease caused by abnormal activation of the complement system, leading to harmful deposits in the kidneys and frequent recurrence after kidney transplants.
- More than half of kidney transplant recipients experience recurrence of this disease, which is the second most common cause of graft loss after organ rejection.
- Current treatment options include corticosteroids and mycophenolate mofetil, but new anti-complement drugs are being studied, showing promise for improving outcomes in affected transplant patients.
Acellular dermal matrices (ADMs) are biological engineered tissues, which may provide an immunologically inert scaffold in breast reconstruction. Since the literature on imaging features of ADMs is limited, radiologists must be aware of the common imaging appearances of ADM, to differentiate normal conformation from residual or recurrent disease. Our purpose is to review the current role of ADMs in implant-based breast reconstruction, describing the normal imaging findings at ultrasound, mammography, and MRI also considering the possible changes over time.
View Article and Find Full Text PDFSince SARS-CoV-2 spread through China at the end of 2019, COVID-19 has been probably the most difficult challenge in the last decades for healthcare systems all around the world, still representing a danger for fragile patients with different comorbidities. Chronic dialysis patients affected by COVID-19 experienced severe disease with a higher mortality rate compared to the general population. Morbidity and mortality of this severe acute respiratory syndrome depend on both acute respiratory failure and systemic immunological involvement with consequent inflammation-mediated injury.
View Article and Find Full Text PDFThe beneficial impact of dietary fiber on the prevention and management of several chronic conditions associated with aging, including diabetes, neurodegenerative, cardiovascular diseases, and cancer, is well-known. High fiber intake has been associated with reduced inflammatory mediators counteracting the low-grade chronic inflammation typical of older age. In addition, dietary fiber improves postprandial glucose response and insulin resistance.
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