Publications by authors named "G C Barbieri"

Background And Purpose: The safety and effectiveness of endovascular techniques in elderly patients with large vessel occlusion (LVO) remain controversial. We investigated the angiographic and clinical outcomes of nonagenarians treated with different endovascular techniques using a balloon guide catheter (BGC), distal aspiration catheter (DAC), and/or stent retriever (SR).

Methods: We analyzed the data from the Registry of Combined versus Single Thrombectomy Techniques (ROSSETTI) of consecutive nonagenarian patients with anterior circulation LVO and compared the outcomes of those treated with BGC+noDAC+SR (101-group), BGC+DAC+SR (111-group), and noBGC+DAC+SR (011-group).

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Background: Kidney diseases are a public health burden but are poorly investigated in the general population. In light of inadequate survey tools, we developed a novel questionnaire for use in population-based studies, to retrospectively assess kidney diseases.

Methods: The questionnaire covered general kidney diseases, reduced kidney function, and renal surgeries.

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The recycling of biowaste from municipal wastewater treatment plants (WWTPs) in agriculture represents a circular economy-driven source of water and nutrients to support food system sustainability. However, biowaste may represent the source of emerging hazards of anthropogenic and animal origin that can transfer from agricultural soils to related food production, posing a risk to consumers' health, as in the case of outbreaks due to the consumption of ready-to-eat leafy vegetables contaminated with pathogenic . From this perspective, we propose a combined strategy based on both classical methods and culture-independent metagenomics approaches to identify microbial hazards relevant to foodborne diseases in WWTP-related biowastes.

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  • * Cornea xenotransplantation using porcine corneas is a potential solution due to the cost-effectiveness and biological compatibility, but there are ethical issues and immune rejection concerns that need to be addressed.
  • * Recent advancements in genetic engineering and new immunosuppressive techniques are showing promise in increasing the success rate of porcine corneal transplants, highlighting the need for ongoing research to improve safety and effectiveness.
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  • - Group B Streptococcus (GBS) can switch from being harmless to causing serious infections, particularly in newborns and the elderly, based on how it manages its virulence factors.
  • - The study focuses on the SaeRS two-component system, which helps regulate the expression of specific virulence factors that allow GBS to invade host cells and persist during infections.
  • - Findings show that while activating SaeRS can enhance GBS's ability to adhere to and invade host tissues, it may reduce overall virulence, highlighting the complex balance in bacterial pathogenesis.
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