Patient-centred outcome measures for oncological surgery: a narrative review.

Introduction: Peri-operative medicine is becoming increasingly relevant in the context of managing frail patients with cancer. This paper outlines how demographic shifts in populations are affecting cancer incidence and frailty rates, the relevance this holds to the management of cancer care, and the outcome measures that should be used to gauge best clinical practice to ensure patient-centred care.

Methods: A targeted literature review was conducted using the search terms 'surgical oncology', 'outcomes', 'frailty', 'quality of life' and 'end of life' from 10 to 17 June 2024.

Pupilmate: A do-it-yourself frugal pupilometer.

The pupillary direct and consensual reflex is an important non-invasive quick assessment of the neurological state of the eye. Currently, there is no cheap and affordable recording tool for screening and documentation of a relative afferent pupillary defect. We describe how to construct a frugal, do-it-yourself handheld scotopic binocular pupillometer device called Pupilmate.

Acceptability of Microbiota-Directed Complementary Foods in Treating Indian Children with Moderate Acute Malnutrition: eACT-MAM Pre-Proof-of-Concept Study.

Background: In India, currently, there are no standard guidelines for the management of moderate acute malnutrition (MAM). Previous research in Bangladesh has shown that children with MAM have impaired gut microbiota development, and microbiota-directed complementary foods (MDCF) can potentially repair their gut microbiota.

Objectives: The objectives of this study were to evaluate the acceptability and safety of supplementing shelf-stable formulation of MDCF in Indian children with MAM as compared with a locally prepared ready-to-use supplementary food (RUSF) in 3 geographically distinct Indian populations and to establish and pilot systems of intervention delivery, collection, transport, and storage of stool samples using stringent protocols.

α-Glucosidase Inhibiting Chromene Derivatives from Ageratum conyzoides L. Essential Oil Extracted via NADES-Assisted Hydrodistillation.

This work employed a green approach utilizing natural deep eutectic solvent (NADES)-assisted hydrodistillation for EO extraction from the aerial part of Ageratum conyzoides. Out of seven deep eutectic combinations used, glycerol-lactic acid (GLY:LA) (1 : 1) mixture significantly enhanced the yield from 0.78 mg/g (water as extraction media) to 1.