Publications by authors named "G Bushati"
Article Synopsis
- CD74, traditionally known for its role in MHC II-mediated antigen presentation, also acts as a high-affinity receptor for the inflammatory cytokine macrophage migration inhibitory factor (MIF), impacting various diseases, including cancer and COVID-19.
- Recent research shows that although CD74 is present intracellularly in resting human CD4 T cells, its expression increases upon T-cell activation, where it interacts with CXCR4 and facilitates MIF-induced T-cell migration.
- In a study of COVID-19 patients, elevated CD74 surface expression on CD4 and CD8 T cells was noted in those with severe symptoms, suggesting its potential role in disease severity and as a functional receptor linked to MIF signaling.
Microbiological pollution of drinking water is a major health problem in the suburbs of the Albanian capital. Intermittent supply and contamination, resulting in several gastrointestinal manifestations, are the main concerns for the population and health workers. The risk of outbreaks of water-borne diseases is high.
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