Estrogen regimen of women with endometrial carcinoma. A retrospective case-control study at Radiumhemmet.

In order to detect a possible association between exogeneous estrogens and endometrial cancer under Swedish circumstances, the previous use of estrogens among 622 cases of endometrial cancer 1974-77 has been compared with that of the average female population, represented by a randomly selected sample of 1 866 contemporaries to the cancer cases. Among women aged 50-69 years, 6-36 months of use of 'natural' and/or to a much lesser extent 'synthetic' estrogens was equally common in the two groups. However, starting in 1976, 3-6 years of use became increasingly more common among cancer cases.

Urethral pressure profile at pubococcygeal repair for stress incontinence.

The influence of pubococcygeal repair on the urethral pressure profile as well as the cure rate, technical operative results and side-effects have been studied in 16 severely stress-incontinent patients. The patients were followed during the first postoperative year in order to detect the possible long-term effects of devascularization, denervation and scarring on the urethral tone. Examination, using simultaneous urethrocystometry with recording of the urethral pressure profile at rest was undertaken preoperatively, 3 months postoperatively and one year postoperatively.

Cultures from different parts of the urethra in female urethral syndrome.

It is a common belief that the female urethral syndrome is an infectious disease, caused by ascending vestibular microorganisms or bacteria harboured in the paraurethral glands. To study the flora of different parts of the urethra in patients with urgency, cultures were obtained in 36 cases from the proximal urethra, the external urethral opening, the distal urethra after paraurethral massage and from the upper vagina for comparison. All locations were dominated by lactobacillae.

Mental factors influencing recurrence of stress incontinence.

At a recent follow-up of 51 women operated on for stress incontinence, there was an astonishingly high discrepancy between symptoms claimed by the patients and signs found by the physician. To examine the influence of certain mental factors on the recurrence of stress incontinence, the patients in the above-mentioned follow-up were tested with the Eysenck Personality Inventory test and the Sabbatsberg Depression Self-rating Scale test. The women with symptoms but no objective signs of stress incontinence showed a higher degree of both neuroticism and depression than the women of perfect health.