Publications by authors named "G Bryson"

Introduction: The autoimmune encephalitides (AE) are a heterogeneous group of neurological disorders with significant morbidity and healthcare costs. Despite advancements in understanding their pathophysiology, uncertainties persist regarding long-term prognosis and optimal management. This study aims to address these gaps, focusing on immunotherapeutic strategies, neoplastic associations and functional outcomes.

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  • Patients undergoing open radical cystectomy have a high risk of needing blood transfusions, and the study investigates the use of tranexamic acid (TXA) to potentially reduce this risk.
  • The TACT trial was a randomized, double-blind study conducted in 10 academic centers from 2013 to 2021, involving patients scheduled for this type of surgery due to bladder cancer.
  • Results showed no significant difference in RBC transfusion rates between the TXA group and the placebo group, with both groups needing transfusions at similar rates up to 30 days post-surgery.
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Sexual minority (SM) men's sexual revictimization (SR; i.e. experiences of adult victimization among childhood sexual abuse survivors) is an understudied topic despite evidence that SM men are disproportionately impacted by sexual violence (SV) over the life course.

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  • The study focused on whether a home-based exercise program combined with nutritional guidance (prehabilitation) improves disease-free survival and return to treatment for older cancer patients with frailty compared to usual care.* -
  • Out of 204 participants, results showed that the prehabilitation group and control group had similar rates of death or cancer recurrence (11% each), and slightly more patients returned to treatment in the prehabilitation group (29% vs. 23%).* -
  • Ultimately, the research found no significant advantage of exercise prehabilitation on disease-free survival or treatment return, suggesting that future studies may need to be larger to detect meaningful effects.*
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