Publications by authors named "G Brisca"

Background: pneumonia (PJP) has high mortality rates in immunocompromised children, even though routine prophylaxis has decreased in incidence. The aim of this case series is to present the radiological and clinical pathway of PJP in a pediatric population.

Description Of Cases: All PJP cases in non-HIV/AIDS patients diagnosed at Istituto Giannina Gaslini Pediatric Hospital in Genoa (Italy) from January 2012 until October 2022 were retrospectively evaluated.

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Article Synopsis
  • - A-DRESS (Allopurinol-induced Drug Reaction with Eosinophilia and Systemic Symptoms) is more common in adults but rare in children, with a case reported in a 16-year-old male with a severe reaction, including fever, rash, shock, and eosinophilia.
  • - The patient's condition improved after stopping allopurinol and receiving treatment with intravenous immunoglobulins (IVIG) and corticosteroids, highlighting the importance of quick intervention.
  • - This case emphasizes the need for early diagnosis of DRESS in pediatric patients and suggests that IVIG may play a significant role in their treatment.
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The aim of this study was to describe the 2022-2023 bronchiolitis epidemic season (the second after COVID-19 pandemic and the first without social restriction), focusing on patients discharged home from a pediatric emergency department (PED) and on those revisited within 72 h. We performed a retrospective observational study in an Italian tertiary care children's hospital, reviewing PED accesses from 1 October 2022 to 31 March 2023. The number of hospitalizations for bronchiolitis was extracted from hospital discharge forms.

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We describe an atypical case of Whipple disease exclusively involving the spinal cord in an adolescent receiving immunosuppressive therapy for systemic lupus erythematosus. The diagnosis was particularly difficult since lupus and Whipple disease can present similar clinical features and the patient's prolonged contact with sewage was initially not mentioned. A literature review of the clinical, imaging, diagnostic, and therapeutic challenges of Whipple disease is also performed.

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