Publications by authors named "G Brigante"
This is the first episode of a series of four discussions on the differences between males and females, in apparently non-andrological fields. You will read the transcript of discussions that actually took place at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogues of ancient Greece. In this episode, the role of testosterone in gender differences in criminal behavior will be explored.
View Article and Find Full Text PDFObjective: Decreased survival and higher cardiovascular morbidity have been recently reported in a UK cohort of 61 RTHβ patients, but there is no evidence from other countries.
Design: Retrospective cohort study from an historical group of 284 Italian RTHβ patients, diagnosed between 1984 and 2023.
Methods: We collected data on diagnosis of 284 cases and longitudinal data of 249 RTHβ who carried heterozygous pathogenic variants in the THRB gene.
Context: The utility of thyroglobulin (Tg) in the follow-up of differentiated thyroid cancer (DTC) patients has been well-documented. Although third-generation immunoassays have improved accuracy, limitations persist (interfering anti-Tg antibodies and measurement variability). Evolving treatment strategies require a reevaluation of Tg thresholds for optimal patient management.
View Article and Find Full Text PDFObjective: Many cases of subacute thyroiditis (SAT) have been described related to SARS-CoV-2 infection, but no prospective data about follow-up are known. This prospective, longitudinal, 3-year, multicentre study aims to explore the clinical peculiarities and outcome of SAT in relation to SARS-CoV-2 infection, ascertained with antibody dosage.
Methods: All patients receiving SAT diagnosis from November 2020 to May 2022 were enrolled.
Article Synopsis
- - The study investigated Campylobacter infections in Italy from 2017 to 2021, analyzing data from 19 hospitals across 13 regions to understand the epidemiology and antibiotic resistance patterns.
- - A total of 5,419 Campylobacter isolates were analyzed, with C. jejuni being the most prevalent species, and the majority of infections were found in males and outpatients; resistance to common antibiotics like ciprofloxacin and tetracyclines was notably high but showed a decrease over the study period.
- - The findings indicate that while resistance to fluoroquinolones and tetracyclines is decreasing, it remains significant, whereas macrolides show consistent effectiveness against Campylobacter in Italy.