Publications by authors named "G Boccuzzi"
Article Synopsis
- Percutaneous coronary intervention (PCI) has greatly improved treatments for coronary artery disease, but in-stent restenosis (ISR) remains a significant issue, especially when complicated by calcification.
- Various techniques exist for treating calcified ISR, including super-high-pressure balloon dilation, atherectomy methods, and intravascular lithotripsy (IVL).
- This case report discusses a patient with severe, calcified ISR in a large artery, showcasing the use of shockwave lithotripsy combined with balloon dilation to improve stent expansion, highlighting the effectiveness of innovative approaches for difficult ISR cases.
Pulmonary embolism (PE) is commonly treated primarily with pharmacological therapy, while advanced reperfusion therapies (transcatheter or surgical) are considered only in cases of contraindications or failure of standard therapies. Treatment algorithms vary depending on the patient's risk, with patients at intermediate or high risk potentially requiring evaluation for such advanced reperfusion therapies. Critical scenarios, such as contraindications to systemic thrombolysis or failure of pharmacological protocols, necessitate the activation of a multidisciplinary pulmonary embolism response team (PERT) and prompt therapeutic escalation.
View Article and Find Full Text PDFNon-invasive physiological assessment of intermediate coronary stenoses from plain angiography through artificial intelligence: the STARFLOW system.
Eur Heart J Qual Care Clin Outcomes
October 2024
Background: Despite evidence supporting use of fractional flow reserve (FFR) and instantaneous waves-free ratio (iFR) to improve outcome of patients undergoing coronary angiography (CA) and percutaneous coronary intervention, such techniques are still underused in clinical practice due to economic and logistic issues.
Objectives: We aimed to develop an artificial intelligence (AI)-based application to compute FFR and iFR from plain CA.
Methods And Results: Consecutive patients performing FFR or iFR or both were enrolled.
Article Synopsis
- Pregnancy-Associated Spontaneous Coronary Artery Dissection (P-SCAD) is the leading cause of heart attacks during and after pregnancy, with the study examining its presentation, treatment, and outcomes based on a review of 253 studies involving 316 patients.
- Most patients were postpartum (79.6%), with common symptoms including ST-elevation myocardial infarction, and severe complications like cardiac arrest occurring in a significant number.
- The study found a relatively low mortality rate of 4.1%, but a notable recurrence rate (23.4%) after initial treatment, suggesting a need for better diagnostic methods and treatment guidelines for this complex condition.
Article Synopsis
- Left atrial appendage (LAA) occluder embolization is a rare but critical complication occurring mostly within the first 24 hours after the procedure, with data collected from 67 centers on 108 patients.
- The management strategies included attempting percutaneous retrieval in 75% of cases, while 21.3% of patients underwent surgery without prior attempts, highlighting significant mortality rates associated with multiple retrieval attempts.
- Overall, a major adverse event rate of 43.5% was observed, underscoring the serious risks, including death, particularly following unsuccessful retrievals.