Obesity and Infertility: A Metabolic Assessment Strategy to Improve Pregnancy Rate.

Background: The metabolic global approach is a multidisciplinary intervention for obese women before undergoing assisted reproductive techniques, with the goal of improving fertility and decreasing adverse pregnancy outcomes. The objective of this study was to evaluate the impact of the metabolic global approach on pregnancy rate.

Methods: This retrospective cohort study included 127 women and was conducted at the Centre hospitalier de l'Université de Montréal fertility center.

Parenting narcissus: what are the links between parenting and narcissism?

Previous theorizing by clinical psychologists suggests that adolescent narcissism may be related to parenting practices (Kernberg, 1975; Kohut, 1977). Two studies investigated the relations between parenting dimensions (i.e.

[Impact of sperm DNA fragmentation on ART outcome].

We have used the sperm chromatin structure assay (SCSA) test in order to determine if correlations can be found between sperm DNA fragmentation and spermogram parameters. Only necrospermia and DNA fragmentation index are strongly correlated (P<0.0001).

Sperm DNA fragmentation: threshold value in male fertility.

Background: The extent of sperm DNA fragmentation, which can be measured by the TUNEL assay, is one of the determinants of male fertility. However, the clinical application of this test to in-vivo situations is difficult owing to the absence of a statistically validated threshold value.

Methods: The aim of this study was to compare the results of TUNEL assay applied to semen samples from men of proven fertility (n = 47) and patients from an infertile population (n = 66), in order to establish a discriminating threshold value.

[Sperm DNA integrity as diagnosis and prognosis element of male fertility].

Recent progress in reproductive biology has improved comprehension physiology of the spermatozoa and on the fertilization mechanisms. This new knowledge has carried out the elaboration of tests on male fertility based on sperm genomic integrity. This review presents some of these techniques and brings a reflexion element on the application and use of sperm DNA integrity in the investigation of male fertility.