Electrophysiological Insights into Alzheimer's Disease: A Review of Human and Animal Studies.

This review highlights the crucial role of neuroelectrophysiology in illuminating the mechanisms underlying Alzheimer's disease (AD) pathogenesis and progression, emphasizing its potential to inform the development of effective treatments. Electrophysiological techniques provide unparalleled precision in exploring the intricate networks affected by AD, offering insights into the synaptic dysfunction, network alterations, and oscillatory abnormalities that characterize the disease. We discuss a range of electrophysiological methods, from non-invasive clinical techniques like electroencephalography and magnetoencephalography to invasive recordings in animal models.

Bibliometric analysis of the usage of tenecteplase for stroke.

Introduction: In recent years, tenecteplase has been competing with alteplase as a treatment for acute ischemic stroke given its ease of administration, lower dosage, cost-effectiveness, and better safety data. This paper seeks to analyze academic literature regarding the burgeoning usage of tenecteplase as a treatment for acute ischemic stroke across the world.

Method: The Web of Science database was used to collect the data from articles containing the keywords "Tenecteplase" and "Stroke" published from 1999 to 2023.

History of the Ophthalmoscope.

This article will describe the history of an important tool: the ophthalmoscope. The evolution of the ophthalmoscope will be analyzed, beginning with its first historical reference and detailing every iteration of the instrument leading up to the version we know today. This article will elaborate on the significance of the ophthalmoscope as a vital instrument for performing eye fundus examinations and explain why it is a staple accouterment in the field of ophthalmology.

Spatial navigation: Alzheimer's pathology disrupts movement-based navigation.

All animals use two different strategies to navigate: idiothetic or movement-based navigation, and allothetic or landmark-based navigation. A new study reveals that compromised idiothetic navigation underlies disrupted grid cell coding in an early stage Alzheimer's disease mouse model.