Publications by authors named "G Berezhnoy A"
Objective: To analyze the effect of interventional surgery on treatment efficacy and inflammatory cytokine (ICK) levels in diabetic patients with peripheral vascular disease (PVD).
Methods: A total of 116 diabetic patients with PVD admitted to the Second Affiliated Hospital of Guangzhou Medical University from August 2020 to March 2022 were selected for this retrospective analysis. Patients were divided into two groups: 58 patients receiving conventional medication were assigned to the control group, while 58 patients receiving interventional surgery in addition to conventional medication were assigned to the research group.
People with chronic pain mitigate their suffering by the action of opioids. Adverse reactions aside, opioids are not exempt from potential complications like addiction and abuse, which have posed a global public health problem lately. Finding new therapeutic strategies to improve analgesia and to reduce opioid side effects has become a priority.
View Article and Find Full Text PDFCaprine livestock are significant reservoirs of the complex (MTBC), contributing to tuberculosis (TB) transmission among animals and humans. The P22 protein immunocomplex (P22PI), derived from bovine tuberculin, shows immunostimulating capacity and is used for TB diagnosis. This study assessed the immunogenicity and protective efficacy of P22PI in two groups of goats: 24 naïve goats (12 immunised, 12 controls) from a TB-free herd, and 24 infected goats (12 immunised, 12 controls), referred to as pre-infected animals, from a -infected herd.
View Article and Find Full Text PDFArticle Synopsis
- E-cigarettes are becoming popular as a way for people to quit smoking, but there are concerns about their use alongside traditional cigarettes, particularly among pregnant women, who may face increased health risks.
- A systematic review analyzed data from 18 studies involving nearly 6 million pregnant women, finding that 4.6% of them reported using both e-cigarettes and traditional tobacco.
- The findings suggest that dual use is a significant health issue, highlighting the need for further research and public health measures to inform and protect pregnant women from the risks of tobacco.
Article Synopsis
- - The study aimed to determine how long it takes for intensive lipid-lowering therapy to reduce major adverse cardiovascular events (MACE) in people with established cardiovascular disease (CVD), particularly before and after 2010 when new treatments like PCSK9 inhibitors and ezetimibe were introduced.
- - Researchers reviewed seven randomized controlled trials involving over 92,000 adults and found that it takes about 19.6 months of intensive therapy to prevent one MACE per 100 patients, with variations based on the treatment used.
- - Results showed that before 2010, high-intensity statin therapy required a TTB of 15.2 months, while PCSK9i and ezetimibe therapies had longer TTB