Publications by authors named "G Bens"
Article Synopsis
- Sézary syndrome is a rare and deadly skin cancer, and this study looked into the survival rates and factors affecting outcomes, particularly focusing on the treatment mogamulizumab.
- *The research analyzed data from 339 patients diagnosed between 2000 and 2020 across Europe, highlighting that age over 80 and large-cell transformation worsened survival rates.
- *Results indicated that patients treated with mogamulizumab had significantly lower mortality rates, suggesting it is an effective treatment option for Sézary syndrome.
Article Synopsis
- - Merkel cell carcinoma (MCC) is often linked to the Merkel cell polyomavirus (MCPyV), particularly when the virus integrates into the host's DNA and leads to mutations in the Large T antigen (LT), which is essential for the virus's cancer-causing properties.
- - In recent cases involving MCC combined with skin tumors called trichoblastoma and poroma, researchers found evidence of MCC developing from epithelial cells and identified both mutated and wild-type LT sequences.
- - The findings indicate that some MCC cases may contain intact MCPyV genomes and express certain viral proteins, suggesting a more complex interaction between the virus and cancer than previously understood.