Publications by authors named "G Benchimol"
Article Synopsis
- The study investigates the effects of Zika virus (ZIKV) infection on fertility by analyzing pubertal squirrel monkeys infected with the virus.
- Laboratory tests confirmed the monkeys' susceptibility to ZIKV, showing viremia and reduced testosterone levels, alongside severe testicular damage observed via ultrasound.
- Histopathological analyses revealed significant testicular lesions, including cell degeneration in the seminiferous tubules, suggesting potential negative impacts of ZIKV on male fertility.
Article Synopsis
- The study aimed to assess the feasibility of using dynamic contrast-enhanced MRI (DCE MRI) to evaluate placental blood flow in pregnant women.
- A total of 134 patients participated, and after quality checks, 62 DCE MRIs were analyzed, revealing that fetuses with intrauterine growth restriction (IUGR) had significantly lower placental blood flow compared to those with appropriate growth (AGA).
- The findings suggest that DCE MRI can effectively measure in vivo placental perfusion and highlight alterations in placental function in pregnancies affected by IUGR, providing baseline data for future research.
Article Synopsis
- This study compares the prognostic performance of two cancer assessment scores, Residual Cancer Burden (RCB) and Neo-Bioscore, in 750 women with invasive breast cancer who received neoadjuvant chemotherapy.
- The analysis found that RCB was generally more effective than Neo-Bioscore in predicting disease-free and overall survival, particularly in triple-negative breast cancer, although both scores were associated with patient outcomes.
- Adding factors like lymphovascular invasion and pre-/post-neoadjuvant chemotherapy tumor-infiltrating lymphocytes improved the performance of both scoring systems, but RCB's simpler classification system makes it easier to apply in clinical settings.
