Structural Characterization of Encapsulin in Complex with Dye-Decolorizing Peroxide.

(Mtb) is the causative agent of tuberculosis, the world's deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host's defenses and survive intracellularly. Mtb's oxidative stress response enables Mtb to survive within activated macrophages, an environment with reactive oxygen species and low pH.

Proof-of-concept study of anti-Fel d 1 IgY antibodies in cat food using the MASK-air app.

Background: An innovation to better manage cat-allergic patients utilises anti-Fel d 1 IgY antibodies to neutralise Fel d 1 after its production by the cat. However, there is no published study showing its clinical efficacy in humans in a home setting. A longitudinal, open-label, proof-of-concept study was carried out to approach clinical efficacy of the cat food in cat-allergic patients.

Valitrack study: Objective evaluation of medical compression wearing time and patient activity with the Accutrack by Sigvaris Group sensor.

Introduction: Objective measurement of compliance is mandatory to evaluate therapeutic effects and clinical benefits of medical compression stockings. This Valitrack study evaluates the Accutrack sensor equipped with an accelerometer. The evaluation is done under controlled and free conditions and during washing.

From Transient to Stationary Transport in Porous Networks under Various Adsorption Conditions and Kinetics.

We investigate the interplay between adsorption and transport in a two-dimensional porous medium by means of an extended Lattice Boltzmann technique within the Two-Relaxation-Time framework. We focus on two canonical adsorption thermodynamics and kinetics formalisms: (1) the Henry model in which the adsorbed amount scales linearly with the free adsorbate concentration and (2) the Langmuir model that accounts for surface saturation upon adsorption. We simulate transport of adsorbing and nonadsorbing particles to investigate the effect of the adsorption/desorption ratio , initial free adsorbate concentration , surface saturation Γ, and Peclet numbers Pe on their dispersion behavior.

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus.

One of the main causes of epilepsy is an infection of the central nervous system (CNS); approximately 8% of patients who survive such an infection develop epilepsy as a consequence, with rates being significantly higher in less economically developed countries. This work provides an overview of modeling epilepsy of infectious etiology and using it as a platform for novel antiseizure compound testing. A protocol of epilepsy induction by non-stereotactic intracerebral injection of Theiler's murine encephalomyelitis virus (TMEV) in C57BL/6 mice is presented, which replicates many of the early and chronic clinical symptoms of viral encephalitis and subsequent epilepsy in human patients.