Publications by authors named "G Bastien"

Introduction: Drug-related hospital admissions (DRAs) can account for 5%-40% of total hospital admissions in older adults, with a significant proportion deemed preventable. To increase the detection of DRAs, in 2021, a revised trigger tool listing 21 frequent causes of admissions and medications at risk was proposed. This study aimed to describe DRAs using this trigger tool in a French acute geriatric ward and to assess the performance of the tool.

View Article and Find Full Text PDF
Article Synopsis
  • A systematic review and meta-analysis were conducted to evaluate the effectiveness and safety of naltrexone as a treatment for amphetamine-type stimulant use disorder (ATSUD) using data from several medical databases.
  • Five randomized placebo-controlled trials involving 419 participants were analyzed, showing no significant difference in outcomes such as reductions in stimulant use, treatment retention, or cravings between naltrexone and placebo groups.
  • The study concluded that there is insufficient evidence to support the use of naltrexone alone for treating ATSUD, highlighting the need for more research to find effective pharmacotherapies alongside psychosocial treatments.
View Article and Find Full Text PDF

The study of magnetic frustration in classical spin systems is motivated by the prediction and discovery of classical spin liquid states. These uncommon magnetic phases are characterized by a massive degeneracy of their ground state implying a finite magnetic entropy at zero temperature. While the classical spin liquid state is originally predicted in the Ising triangular lattice antiferromagnet in 1950, this state has never been experimentally observed in any triangular magnets.

View Article and Find Full Text PDF

Viruses of microbes are ubiquitous biological entities that reprogram their hosts' metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental health. Advances in genome sequencing have led to the discovery of millions of novel viruses and an appreciation for the great diversity of viruses on Earth. Yet, with knowledge of only "who is there?" we fall short in our ability to infer the impacts of viruses on microbes at population, community, and ecosystem-scales.

View Article and Find Full Text PDF

Molecular platforms are essential components of various surface-mounted molecular devices. Here, we document the synthesis of two universal triptycene-based tripodal pedestals featuring terminal alkynes in the axial position. We showcase their versatility by incorporating them into the structures of diverse functional molecules such as unidirectional light-driven molecular motors, photoswitches, and Brownian molecular rotors using standard cross-coupling reactions.

View Article and Find Full Text PDF