Publications by authors named "G Barnett"

Several studies report the benefits and accuracy of using autosegmentation for organ at risk (OAR) outlining in radiotherapy treatment planning. Typically, evaluations focus on accuracy metrics, and other parameters such as perceived utility and safety are routinely ignored. Here, we report our finding from the implementation and clinical evaluation of OSAIRIS, an open-source AI model for radiotherapy image segmentation that was carried out as part of its development into a medical device.

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The rapid advancement and widespread adoption of artificial intelligence (AI) has ushered in a new era of possibilities in healthcare, ranging from clinical task automation to disease detection. AI algorithms have the potential to analyse medical data, enhance diagnostic accuracy, personalise treatment plans and predict patient outcomes among other possibilities. With a surge in AI's popularity, its developments are outpacing policy and regulatory frameworks, leading to concerns about ethical considerations and collaborative development.

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Article Synopsis
  • A study was conducted to compare the neurological and radiographic outcomes between patients treated with initial stereotactic radiosurgery (SRS) and those who underwent a second SRS for intracranial arteriovenous malformations (AVMs).
  • Data from 21 medical centers spanning from 1987 to 2022 included a matched comparison of 328 patients in each group, focusing on factors like AVM volume and location.
  • Results indicated similar rates of obliteration and radiation-induced changes between the two groups, suggesting that repeat SRS is as effective as the initial treatment and may not require dose reduction.
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  • * They analyzed data from 535 pediatric patients who underwent SRS, finding that infratentorial AVMs tend to be located deeper in the brain and had higher instances of hemorrhagic presentations compared to supratentorial AVMs.
  • * The results indicated no significant differences in treatment outcomes, like AVM obliteration or post-SRS complications, between infratentorial and supratentorial AVM patients, suggesting SRS has a comparable risk profile for both types.
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