[Validation of Oral Health Impact Profile (OHIP) quality of life questionnaire in Russian patients with evidence of chronic generalized periodontitis].

As part of research project translation and validation of Oral Health Impact Profile (OHIP) quality of life questionnaire has been administered. 25 patients have been interviewed (8 men and 17 women), the average age was 40+/-8 years, with evidence of chronic generalized periodontitis. The clinical picture of the disease development in those patients was common.

[Parodontal tissues reaction to filling of dental root defect with different materials in experiment].

In experimental study on 4 mongrel 4-5 year old dogs under intravenous anesthesia (rometar) after turning back of mucous-periosteum flap and forming artificial defects of hard tissues in the upper third of a dental root the defects were filled with glass-ionomer cement (Ketac-molar, 3M-Espe), composite light cured material (Heliomolar flow, Ivoclar-Vivadent), amalgam with high silver content (Amalcap Plus regular non-Gamma-2, Ivoclar-Vivadent) or with material for dental root perforation closure (PRO-Poot mta, Dentsply). It was found that parodontium reacted to these filling materials by inflammation. The glass-ionomer cement and material for dental root perforation closure had lesser effect on parodontium in comparison with composite and amalgam.

Effects of NOS inhibition on the cardiopulmonary system and brain microvascular markers after intermittent hypoxia in rats.

We previously demonstrated that rats subjected to intermittent hypoxia (IH) by exposure to 10% O(2) for 4 h daily for 56 days in a normobaric chamber, developed pulmonary hypertension, right ventricular hypertrophy and wall-thickening in pulmonary arterioles, compared with normoxic (N) controls. These changes were greater in rats subjected to continuous hypoxia (CH breathing 10% O(2) for 56 days). Cerebral angiogenesis was demonstrated by immunostaining with glucose transporter 1 (GLUT1) antibody, in viable vessels, in CH and to a lesser degree in IH.

[Oral cavity manifestations of gastroesophageal reflux disease].

The aim of the study was to investigate changes in the oral cavity and the gastroesophageal zone of the patients receiving rabeprazol, a proton pump inhibitor (PPI). The subjects were 88 patients with gastroesophageal reflux disease (GERD), who had changes in the oral cavity typical of this disease. The patients were divided into four groups.