Publications by authors named "G Barbara"
Munchausen syndrome by proxy is extremely difficult to diagnose. A case is presented of a 17-month-old girl who repeatedly sustained cold burns caused by a spray deodorant and inflicted by her mother. A comprehensive medical investigation, including blood assessments, skin biopsies and imaging were inconclusive.
View Article and Find Full Text PDFInternational consensus statement on microbiome testing in clinical practice.
Lancet Gastroenterol Hepatol
December 2024
There is growing interest in the potential exploitation of the gut microbiome as a diagnostic tool in medicine, but evidence supporting its clinical usefulness is scarce. An increasing number of commercial providers offer direct-to-consumer microbiome diagnostic tests without any consensus on their regulation or any proven value in clinical practice, which could result in considerable waste of individual and health-care resources and potential drawbacks in the clinical management of patients. We convened an international multidisciplinary expert panel to standardise best practices of microbiome testing for clinical implementation, including recommendations on general principles and minimum requirements for their provision, indications, pre-testing protocols, method of analyses, reporting of results, and potential clinical value.
View Article and Find Full Text PDFArticle Synopsis
- * The study indicates that HBV causes HCC through integration into the host genome, inflammation, and immune response changes, while HDV worsens liver damage and increases HCC risk, with emerging therapies like Bulevirtide showing potential.
- * Despite progress in treatments reducing HBV-related HCC, HDV remains a significant challenge with limited options, highlighting the need for continued research on effective therapies and understanding the role of HDV in HCC development.
Article Synopsis
- Colonoscopy is important for diagnosing and treating conditions, and effective bowel cleansing is crucial, but there's no standard preparation for children.
- A systematic review of six studies compared the effectiveness and safety of polyethylene glycol (PEG) and sodium picosulfate (SPMC) for this purpose, finding both to be effective.
- SPMC was generally preferred for its better acceptability and compliance, resulted in fewer instances of needing a nasogastric tube, and a split-dose preparation was found to be more effective than a day-before regimen.