Publications by authors named "G Bar-Sela"
: This case report details the innovative use of selective internal radiation therapy (SIRT) with Yttrium-90 resin microspheres to treat a 73-year-old woman with a solitary fibrous tumor (SFT), a rare and challenging tumor type. SFTs often present significant treatment difficulties, especially in cases of recurrence or metastasis, as systemic therapies typically show limited effectiveness. This report explores SIRT as an alternative therapeutic approach for SFTs with liver metastasis.
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- Conjunctival melanoma, a rare type of ocular melanoma, has some genetic similarities to both skin and mucosal melanoma and presents unique treatment challenges when advanced or metastatic.
- The FDA recently approved the combination treatment Nivolumab/relatlimab (Opdualag) for metastatic melanoma, showing improved survival rates in earlier treatment stages without significant safety concerns, but its effectiveness in conjunctival melanoma is still unknown.
- In a case study, an 87-year-old woman with advanced conjunctival melanoma showed a near-complete clinical response after just one cycle of Opdualag, although treatment was limited to four cycles due to her worsening dementia.
Background: The 12-gene Oncotype DX Colon Recurrence Score® result quantifies the recurrence risk in stage II/III colon cancer (CC). This real-world study investigated stage II CC patients whose treatment decisions incorporated the Recurrence Score® (RS) result.
Materials And Methods: This retrospective analysis of a prospectively designed cohort included all stage II, mismatch repair-proficient CC patients who underwent 12-gene testing through Clalit between January 2011 and December 2016 and had available data with a minimum 3-year follow-up.
This study investigates breast cancer survival rates between 2000 and 2022 in northern Israel, focusing on ethnicity, socioeconomic status, age at diagnosis, and the Charlson Comorbidity Index. Analyzing data from Clalit Health Services, we studied 8,431 breast cancer patients (6,395 Jewish, 2,036 Arab). We compared five- and ten-year survival rates across different demographics.
View Article and Find Full Text PDFUnlike the intense research effort devoted to exploring the significance of heparanase in cancer, very little attention was given to Hpa2, a close homolog of heparanase. Here, we explored the role of Hpa2 in breast cancer. Unexpectedly, we found that patients endowed with high levels of Hpa2 exhibited a higher incidence of tumor metastasis and survived less than patients with low levels of Hpa2.
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