Publications by authors named "G Bagaturiya"

Article Synopsis
  • Recent studies have established a clear link between the structural design of drug compounds and their biological effectiveness, highlighting the importance of stereoisomers in both therapeutic outcomes and potential side effects.
  • The use of computational methods, particularly Quantitative Structure-Activity Relationships (QSAR) alongside molecular modeling, has become essential in modern drug discovery, allowing for computer-based drug searches before moving to lab experiments.
  • With over 101 million known organic compounds and more than 25,000 recognized biological activities, in silico methods are increasingly vital for efficiently screening and identifying promising drug candidates.
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According to the experimental data a triterpene alcohol betulin have anti-inflammatory, wound- and burn-healing activity. Previous data reports, that betulin was used in not less than 5% concentrations. That is why studying less concentrations is of major interest.

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Depression is one the most common form of mental diseases. Due to epidemiological studies, it is common in different age groups including young people. Depression pathogenesis from the point of system perspective view consists of morphofunctional and pathopsychological components.

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The article presents the results of a multicenter study of the etiology, antibiotic sensitivity and pharmacoepidemiology of infective endocarditis in the Russian Federation. The purpose of this study is to analyze the current practice of management of patients with infective endocarditis in conditions of low frequency of etiologically significant pathogens in the Russian Federation. The study included patients of both sexes of all age groups with definite and probable infective endocarditis.

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Thyroid hormones can exert responses in various immune cells affecting several inflammation-related processes. The interactions between the endocrine and immune systems have been shown to contribute to pathophysiological conditions. Aim of study - to answer the question if hyper- or/and hypothyroid state can be as provoking factor for inflammation in colon.

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