Publications by authors named "G Badlani"
Local tissue response to a C-X-C motif chemokine ligand 12 therapy for fecal incontinence in a rabbit model.
Am J Physiol Gastrointest Liver Physiol
January 2025
This study aimed to determine if local injection of CXCL12 reduces sphincter fibrosis, restores sphincter muscle content, vascularization, and innervation, and recruits progenitor cells in a rabbit model of anal sphincter injury and incontinence. Adult female rabbits were assigned to 3 groups: uninjured/no treatment (control), injured/treated (treated), and injured/no treatment (untreated) (n=4 each). Injured groups were anesthetized and a section of external anal sphincter was removed at the 9:00 o'clock position.
View Article and Find Full Text PDFObjective: This study aims to compare the long-term outcomes of Aquablation for small-to-moderate (30-80 cm) prostates with the outcomes for large (80-150 cm) prostates at 5-year follow up.
Methods: The Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue (WATER; NCT02505919) is a prospective, double-blind, international clinical trial encompassing 116 patients, examining Aquablation versus transurethral resection of the prostate (TURP) for LUTS/BPH in prostates sized between 30 and 80 cm. In parallel, WATER II (W-II; NCT03123250), a prospective, multicentre, single-arm international clinical trial, explores Aquablation outcomes in prostates ranging from 80 to 150 cm.
Prevalence and Clinical Correlates of Endometriosis in Patients With IC/BPS.
Urogynecology (Phila)
February 2025
Article Synopsis
- Interstitial cystitis/bladder pain syndrome (IC/BPS) is a complex disorder that poses challenges in diagnosis and treatment, particularly when considering overlaps with conditions like endometriosis.
- A study involving 533 female patients found that 20.3% had concurrent endometriosis, which was linked to younger age and various nonurological symptoms such as chronic pelvic pain and fibromyalgia.
- The results suggest that recognizing endometriosis in IC/BPS patients could lead to more targeted treatments by addressing both bladder and systemic pain issues.
Objective: To explore how changes in planned retirement age, practice setting, and physician productivity may impact the workforce shortage in urology.
Methods: We compared data between the 2015 and 2022 American Urological Association census, a specialty-wide annual survey which collects data on demographics, practice patterns, and procedures from a representative sample of U.S.