Publications by authors named "G BROOKS"
The Mitochondrial Lactate Oxidation Complex: endpoint for carbohydrate carbon disposal.
Am J Physiol Endocrinol Metab
December 2024
The Lactate Shuttle concept has revolutionized our understanding and study of metabolism in physiology, biochemistry, metabolism, nutrition, and medicine. Seminal findings of the Mitochondrial Lactate Oxidation Complex (mLOC) elucidated the architectural structure of its components. Here, we report that the mitochondrial pyruvate carrier (mPC) is an additional member of the mLOC in mouse muscle and C2C12 myoblasts and myotubes.
View Article and Find Full Text PDFGuided by communication accommodation theory, we studied 27 physician reports of patient-physician advanced cancer communication during the COVID-19 pandemic. Advanced cancer communication requires recognizing patients' psychosocial states and collaboratively engaging patients empathetically to develop the shared understanding necessary to guide decision-making. However, physicians found their communication underaccommodated, stemming from personal protection equipment, social distancing, and telemedicine.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed how travel burden for surgical cancer care is affected by rural living, geographic choices, cancer type, and patient mortality outcomes using Medicare data from 2016-2018.
- It found that a significant percentage of cancer patients, particularly those in rural areas, chose to bypass their nearest surgical facility, leading to better survival outcomes post-surgery.
- The research highlights that understanding why rural patients bypass facilities could help improve cancer treatment results and address disparities in cancer care access.