Publications by authors named "G BLANCO"

Accurate identification of decreasing trends is a prerequisite for successful conservation, but can be challenging when immigration compensates local declines in abundance. Here, we show that a potential declining trend driven by low vital rates was overridden and converted into a spectacular increase by massive immigration into the population of a semi-social raptor, the black kite Milvus migrans, breeding in a highly contaminated area near a major landfill. Immigration was promoted by a growing food-base of live prey, coupled with the attraction exerted by the progressive gathering of a large flock of non-breeders at the area, resulting in an "attraction spiral" that lured large numbers of breeders to settle into a contaminated population incapable of self-sustenance.

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Na,K-ATPase is the active ion transport system that maintains the electrochemical gradients for Na and K across the plasma membrane of most animal cells. Na,K-ATPase is constituted by the association of two major subunits, a catalytic α and a glycosylated β subunit, both of which exist as different isoforms (in mammals known as α1, α2, α3, α4, β1, β2 and β3). Na,K-ATPase α and β isoforms assemble in different combinations to produce various isozymes with tissue specific expression and distinct biochemical properties.

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Article Synopsis
  • Ouabain, a hormone, speeds up the progression of autosomal dominant polycystic kidney disease (ADPKD) by increasing cyst area and fibrosis specifically in ADPKD mice due to its interaction with Na,K-ATPase (NKA).
  • Researchers created a mouse model with a knockout of caveolin-1 (CAV1), the main structural protein of caveolae, to investigate the role of these structures in ouabain's effect on ADPKD.
  • The study found that without caveolae, the ADPKD mice did not show increased cyst progression or cellular changes in response to ouabain, indicating that caveolae play a crucial role in NKA signaling and the advancement of
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Understanding the interplay between genetic drift, natural selection, gene flow, and demographic history in driving phenotypic and genomic differentiation of insular populations can help us gain insight into the speciation process. Comparing patterns across different insular taxa subjected to similar selective pressures upon colonizing oceanic islands provides the opportunity to study repeated evolution and identify shared patterns in their genomic landscapes of differentiation. We selected four species of passerine birds (Common Chaffinch Fringilla coelebs/canariensis, Red-billed Chough Pyrrhocorax pyrrhocorax, House Finch  Haemorhous mexicanus and Dark-eyed/island Junco Junco hyemalis/insularis) that have both mainland and insular populations.

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  • The study investigates two surgical approaches (no-touch vs. superior mesenteric artery) in patients undergoing pancreatoduodenectomy for pancreatic ductal adenocarcinoma, focusing on circulating tumor cells during surgery.
  • *Patients were randomly assigned to each group, and samples were taken to measure tumor cell activity at different surgical stages.
  • *Results showed no significant differences in tumor cell mobilization or metastasis-free survival between the two approaches, but patients with tumor cell clusters mobilized during surgery had a higher rate of distant metastases within the first year.
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