Publications by authors named "G B Radhika"

Article Synopsis
  • - A genomic analysis was performed on Attappady Black and Malabari goat breeds in South India using SNP marker data from 48 goats, revealing seven significant regions of selective sweeps that may indicate genetic adaptation related to traits like milk production.
  • - One notable region included the casein cluster and loci linked to milk production on chromosome 6, highlighting its importance for dairy traits in these goat breeds.
  • - Additionally, 13 Panther pathways, such as TGF-beta and GNRHR signaling pathways, were significantly enriched among the 166 identified selective genes, suggesting they play a role in the differences observed between the two goat breeds.
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In the present study, next generation sequencing was employed to identify and explore the differential expression profiles of microRNAs (miRNAs) in peripheral blood mononuclear cells (PBMCs) of crossbred ( x ) and Vechur () cattle in response to the bacterial endotoxin-lipopolysaccharide (LPS). The PBMCs from adult apparently healthy female crossbred cows and Vechur cattle, a native cattle breed of Kerala, India were stimulated with 10 μg/mL of LPS for 6 h. Among the differentially expressed miRNAs, the expression of 13 miRNAs showed statistically significant up regulation while, significant decrease in the expression of 15 miRNAs was noticed in LPS treated PBMCs of Vechur cattle compared to crossbred cows.

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In the present scenario of research, the recycling of inexpensive widely available agricultural waste/biowaste to activate carbon (AC) and procurement of value-added product has significant impact on energy storage systems, particularly in Electrochemical double layer capacitors (EDLCs). Herein, we report the production of KOH activated carbons from different biomass sources such as stem (MAC), seed oil extract cake (PPC), stem (CCC) and floss (ASC) for the said purpose. Initially, the biomass materials were pyrolyzed at 550 °C and then activated with KOH at 800 °C.

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Article Synopsis
  • A study investigated insertion/deletion (InDel) polymorphisms in specific genes related to growth traits in Malabari and Attappady black goats.
  • Body measurements such as length, width, and height were analyzed, and it was found that there were significant differences based on breed, age, and their interaction.
  • The identified InDels showed associations with certain body traits, indicating potential for using these genetic markers in improving goat breeding practices.
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Hypoxia-inducible factor (HIF)-1α is a transcription factor stabilized by hypoxia by inducing or suppressing the homeostatic regulatory gene expression, enabling tissues and cells to survive despite fluctuations in environmental circumstances. As the name implies, hypoxia-inducible factor-1 is secreted not only as a cellular response to hypoxia but also in heat stress and oxidative stress. The goal of this work was to determine the molecular characterisation of the gene coding region as well as the differences in HIF-1αprotein primary structure between Vechur cattle and other cattle breeds in the online databases.

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